The present study attempts to examine the longitudinal impact of a curriculum-based positive youth development program, entitled the Project P.A.T.H.S.(Positive Adolescent Training through Holistic Social Programmes), on adolescent problem behavior in Hong Kong.Using a longitudinal randomized group design, six waves of data were jolly rancher fille
KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m6A reader YTHDC1 protein degradation
Abstract Background Neuroblastoma (NB) patients with amplified MYCN often face a grim prognosis and are resistant to existing therapies, yet MYCN protein is considered undruggable.KAP1 (also named TRIM28) plays a crucial role in multiple biological activities.This study aimed to investigate the relationship between KAP1 and MYCN in NB.Methods Trans